Frovatriptan Succinate Tablets and Propranolol Sustained-Release Capsules
Determining the interaction of Frovatriptan Succinate Tablets and Propranolol Sustained-Release Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The coadministration with propranolol may increase the plasma concentrations of frovatriptan. According to the manufacturer, propranolol increased the peak plasma concentration (Cmax) of frovatriptan (2.5 mg oral dose) by 23% in males and 16% in females. Likewise, the area under the concentration-time curve (AUC) increased by 60% in males and 29% in females. The time to reach peak concentration (Tmax) and half-life were not affected. The mechanism of interaction has not been established. This interaction is unlikely to be of clinical significance.
- "Product Information. Frova (frovatriptan)." Endo Laboratories LLC, Chadds Ford, PA.
Generic Name: frovatriptan
Brand name: Frova
Synonyms: Frovatriptan
Generic Name: propranolol
Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL
Synonyms: Propranolol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Frovatriptan Succinate Tablets-Propranolol Tablets
- Frovatriptan Succinate Tablets-Proprinal
- Frovatriptan Succinate Tablets-Propulsid
- Frovatriptan Succinate Tablets-Propulsid (Cisapride Suspension)
- Frovatriptan Succinate Tablets-Propulsid (Cisapride Tablets)
- Frovatriptan Succinate Tablets-Propylhexedrine
- Propranolol Sustained-Release Capsules-FUDR
- Propranolol Sustained-Release Capsules-Ful-Glo
- Propranolol Sustained-Release Capsules-Fulphila
- Propranolol Sustained-Release Capsules-Fulphila Injection
- Propranolol Sustained-Release Capsules-Fulphila Subcutaneous
- Propranolol Sustained-Release Capsules-Fulvestrant