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Furomide M.D. and Ginseng

Determining the interaction of Furomide M.D. and Ginseng and the possibility of their joint administration.

Check result:
Furomide M.D. <> Ginseng
Relevance: 02.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using furosemide together with ginseng. Using these medications together can cause furosemide to be less effective and can cause fluid retention and high blood pressure to worsen. Call your doctor if you have side effects such as uneven heartbeats, shortness of breath, dizziness, weakness, fainting, or swelling in your extremities. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Ginseng has been reported to induce diuretic resistance in a patient treated with furosemide and cyclosporine. The patient was hospitalized for edema and hypertension approximately 10 days after initiating self-therapy with herbal supplements that included a fairly large quantity of ginseng. While in the hospital, all herbal products were withheld and the patient responded to intravenous furosemide. Following discharge, the patient resumed his herbal regimen and again experienced an episode of edema and hypertension shortly thereafter that was refractory to increases in the furosemide dosage. The patient was readmitted to the hospital, upon which herbal products were discontinued and the patient responded to intravenous furosemide over the next 48 hours. The temporal association of these events strongly suggests a potential drug interaction, however, the exact mechanism is unknown.

MANAGEMENT: Until further data are available, patients treated with furosemide or other loop diuretics should preferably avoid the use of ginseng supplements. The possibility of diuretic resistance should be considered and appropriately monitored if concomitant use is necessary.

References
  • Becker BN, Greene J, Evanson J, Chidsey G, Stone WJ "Ginseng-induced diuretic resistance." JAMA 276 (1996): 606-7
Furomide M.D.

Generic Name: furosemide

Brand name: Lasix, Diaqua-2, Lo-Aqua

Synonyms: Furosemide

Ginseng

Generic Name: ginseng

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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