Fusilev and Sublocade

• Generic Name: levoleucovorin
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Fusilev, Khapzory

Fusilev is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.

Fusilev is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. This medicine may also be used to treat toxic effects of an overdose or methotrexate or certain other medications.

Fusilev is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. This medicine treats only the symptoms of colorectal cancer but does not treat the cancer itself.

Fusilev should not be used to treat anemia that is caused by a lack of vitamin B12.

Fusilev may also be used for purposes not listed in this medication guide.

• Generic Name: buprenorphine
• Dosage Forms: subcutaneous injection
• Other Brand Names: Sublocade, Belbuca, Buprenex, Probuphine, Butrans, Subutex

Sublocade (buprenorphine) is an opioid medication, sometimes called a narcotic.

Sublocade is used to treat opioid addiction. It is not for use as a pain medication.

Sublocade is given to people who have started addiction treatment with an oral form of buprenorphine placed under the tongue or inside the cheek (such as Suboxone or Subutex).

Sublocade is available only in a certified healthcare setting under a special program. You will not be able to give yourself this medicine.