Fuzeon Injection and Rifadin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with rifampin has been shown to have minimal effects on the pharmacokinetics of enfuvirtide. According to the manufacturer, rifampin (600 mg once daily for 10 days) decreased the steady-state trough plasma concentration (Cmin) of enfuvirtide (90 mg twice a day) by 15% in 12 HIV-positive subjects. The peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of enfuvirtide were not affected.

Fuzeon Injection

Generic Name: enfuvirtide

Brand name: Fuzeon

Synonyms: Fuzeon

What is Fuzeon Injection?

Rifadin

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: n.a.

What is Rifadin?