Gadopentetate Intravenous and Indinavir Sulfate

• Generic Name: gadopentetate dimeglumine
• Dosage Forms: injection
• Other Brand Names: Magnevist, Multihance

Gadopentetate injection is a magnetic resonance imaging (MRI) contrast agent that is used to help create a clear picture of the body during an MRI scan. MRI scans are a special kind of diagnostic procedure that use magnets and computers to create images or “pictures” of certain areas inside the body. Unlike x-rays, they do not involve radiation. Gadopentetate is a gadolinium-based contrast agent (GBCA).

Gadopentetate is given by injection before MRI to help diagnose problems in the brain, spine, head, neck, tissues, and other parts of your body.

Gadopentetate is to be given only by or under the direct supervision of your doctor.

• Generic Name: indinavir
• Dosage Forms: n.a.
• Other Brand Names: Crixivan

Treatment of HIV infection in adults, adolescents, and pediatric patients; used in conjunction with other antiretrovirals.

Experts state indinavir not recommended for initial treatment regimens in antiretroviral-naive adults and adolescents because of inconvenient dosing regimen, fluid requirements, and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir with low-dose ritonavir (ritonavir-boosted indinavir) not recommended for initial therapy in antiretroviral-naive adults and adolescents because of fluid requirements and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir (with or without low-dose ritonavir) not recommended for initial treatment regimens in antiretroviral-naive pediatric patients because of high incidence of hematuria, sterile leukocyturia, and nephrolithiasis in children.