Gadoxetate Intravenous and Indinavir Sulfate

• Generic Name: gadoxetate disodium
• Dosage Forms: n.a.
• Other Brand Names: Eovist

Gadoxetate is a magnetic resonance imaging (MRI) contrast agent. Contrast agents are used to help create a clear picture of the body during MRI scans. MRI scans are a special kind of diagnostic procedure. They use magnets and computers to create images or “pictures” of certain areas inside the body. Unlike x-rays, they do not involve ionizing radiation. Gadoxetate is a gadolinium-based contrast agent (GBCA).

Gadoxetate is given by injection before MRI to help diagnose problems in the liver.

Gadoxetate is to be used only by or under the direct supervision of a doctor.

• Generic Name: indinavir
• Dosage Forms: n.a.
• Other Brand Names: Crixivan

Treatment of HIV infection in adults, adolescents, and pediatric patients; used in conjunction with other antiretrovirals.

Experts state indinavir not recommended for initial treatment regimens in antiretroviral-naive adults and adolescents because of inconvenient dosing regimen, fluid requirements, and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir with low-dose ritonavir (ritonavir-boosted indinavir) not recommended for initial therapy in antiretroviral-naive adults and adolescents because of fluid requirements and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir (with or without low-dose ritonavir) not recommended for initial treatment regimens in antiretroviral-naive pediatric patients because of high incidence of hematuria, sterile leukocyturia, and nephrolithiasis in children.