Garamycin Topical and Neomycin Sulfate
Determining the interaction of Garamycin Topical and Neomycin Sulfate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Both gentamicin topical and neomycin belong to the same class of antibiotics known as aminoglycosides. Since the medication in gentamicin topical may be absorbed from the skin, combining it with neomycin may increase the risk of serious side effects reported with aminoglycosides such as hearing loss, respiratory depression, and kidney problems. Patients who may be particularly susceptible include the elderly and those who are dehydrated or have preexisting kidney disease. Gentamicin topical should generally not be used with neomycin in circumstances where significant absorption could occur (for example: application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Let your doctor know immediately if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, or signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Topically applied aminoglycosides may be systemically absorbed and have potentially additive effects with systemically administered aminoglycosides. The risk of oto- and nephrotoxicity and other adverse effects of aminoglycosides may be increased.
MANAGEMENT: Topical preparations containing an aminoglycoside should not be used with other aminoglycosides in circumstances where significant systemic absorption could occur (e.g., application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). The normally recommended dosages of these products should not be exceeded.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: gentamicin topical
Brand name: Garamycin Topical, G-Myticin
Synonyms: n.a.
Generic Name: neomycin
Brand name: Neo-Fradin, Neo-Tab, Mycifradin
Synonyms: Neomycin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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