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Gaviscon Tablet and Lipitor

Determining the interaction of Gaviscon Tablet and Lipitor and the possibility of their joint administration.

Check result:
Gaviscon Tablet <> Lipitor
Relevance: 18.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The manufacturer reports that the coadministration of atorvastatin and Maalox TC (aluminum hydroxide-magnesium hydroxide) led to 35% decrease in plasma concentrations of atorvastatin. However, LDL-C reduction was not altered. The mechanism is unknown, but may be due to a chelation effect. The clinician may want to monitor the patient more closely for a decreased antihyperlipidemic effect.

References
  • "Product Information. Lipitor (atorvastatin)." Parke-Davis, Morris Plains, NJ.
Gaviscon Tablet

Generic Name: aluminum hydroxide / magnesium trisilicate

Brand name: Gaviscon Tablet, Drysol, Hypercare, Xerac AC

Synonyms: Aluminum Hydroxide and Magnesium Trisilicate

Lipitor

Generic Name: atorvastatin

Brand name: Lipitor

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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