Gemtuzumab Intravenous and Valbenazine Tosylate

• Generic Name: gemtuzumab
• Dosage Forms: n.a.
• Other Brand Names: Mylotarg

Gemtuzumab injection is used alone or together with other medicines (eg, cytarabine, daunorubicin) to treat newly-diagnosed CD33-positive acute myeloid leukemia (AML) in adults. It is also used to treat CD33-positive AML that has come back or after other medicines did not work well, in adults and children 2 years of age and older.

Gemtuzumab is an antineoplastic (cancer) medicine. It interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal cells may also be affected by gemtuzumab, other side effects can occur. Before you begin treatment, talk to your doctor about the benefits of gemtuzumab as well as the possible risks of using it.

Gemtuzumab is to be given only by or under the direct supervision of your doctor.

• Generic Name: valbenazine
• Dosage Forms: n.a.
• Other Brand Names: Ingrezza

Treatment of tardive dyskinesia.

Tardive dyskinesia is a hyperkinetic movement disorder associated with prolonged use of antipsychotic agents or other antidopaminergic drugs (e.g., metoclopramide).

Prior to the availability of valbenazine, there was no standard treatment for tardive dyskinesia. Management generally included discontinuance or reducing the dosage of the precipitating drug when possible, switching from a conventional or first-generation antipsychotic to an atypical or second-generation antipsychotic, or switching to clozapine therapy.