About us Contacts Drug interactions: 390 212
Drug search by name

Gemzar and Pms-Etoposide

Determining the interaction of Gemzar and Pms-Etoposide and the possibility of their joint administration.

Check result:
Gemzar <> Pms-Etoposide
Relevance: 21.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

An in vitro test has shown concurrent use of gemcitabine and etoposide to have a synergistic effect. The precise mechanism of the interaction is unknown. The clinical implications of these findings are unknown. Caution for increases in toxicity may be appropriate.

References
  • Nakamura H, Yamaji Y, Fujita T, Fujita J, Takahara J "Synergistic growth inhibition of gemcitabine/cisplatin, and gemcitabine/etoposide on a human lung cancer cell line, RERF-LC-OK (Meeting abstract)." Proc Annu Meet Am Assoc Cancer Res 36 (1995): a24251995
Gemzar

Generic Name: gemcitabine

Brand name: Gemzar, Infugem

Synonyms: n.a.

Pms-Etoposide

Generic Name: etoposide

Brand name: VePesid, Etopophos, Toposar

Synonyms: Etoposide

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction