Gengraf and Spironolactone Oral Suspension
Determining the interaction of Gengraf and Spironolactone Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using cycloSPORINE together with spironolactone. Using these medications together can cause high levels of potassium in your blood. Call your doctor if you have side effects such as slow, fast, or uneven heartbeat, shallow breathing, numbness or tingly feeling, and muscle pain or weakness. A different class of blood pressure medication should be considered. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Cyclosporine may cause hyperkalemia. The concurrent use of potassium-sparing diuretics and cyclosporine may result in or exacerbate hyperkalemia.
MANAGEMENT: The concomitant use of potassium-sparing diuretics and cyclosporine should be avoided. A different class of antihypertensive should be considered.
- Marcy TR, Ripley TL "Aldosterone antagonists in the treatment of heart failure." Am J Health Syst Pharm 63 (2006): 49-58
- "Product Information. Neoral Soft Gelatin Capsules (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
- Perazella MA "Drug-induced hyperkalemia: old culprits and new offenders." Am J Med 109 (2000): 307-14
- "Product Information. Neoral Oral Solution (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Gengraf (Capsules, Modified)
Generic Name: spironolactone
Brand name: Aldactone, CaroSpir
Synonyms: Spironolactone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Gengraf-Spironolactone Tablets
- Gengraf-SpongeBob SquarePants Gummies
- Gengraf-Sporanox
- Gengraf-Sporanox (Itraconazole Capsules (Sporanox))
- Gengraf-Sporanox (Itraconazole Oral Solution)
- Gengraf-Sporanox Capsules
- Spironolactone Oral Suspension-Gengraf (Cyclosporine Capsules, Modified)
- Spironolactone Oral Suspension-Gengraf (Cyclosporine Oral Solution, Modified)
- Spironolactone Oral Suspension-Gengraf Capsules
- Spironolactone Oral Suspension-Gengraf Oral
- Spironolactone Oral Suspension-Gengraf Oral Solution
- Spironolactone Oral Suspension-Genicin