Gengraf Capsules and Griseofulvin Ultramicrosize Tablets
Determining the interaction of Gengraf Capsules and Griseofulvin Ultramicrosize Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cycloSPORINE together with griseofulvin may increase the effects of cycloSPORINE. Contact your doctor if you experience nausea, vomiting, diarrhea, abdominal pain, dizziness, fatigue, or headache. If your doctor prescribes these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Griseofulvin may decrease serum cyclosporine concentrations by an unknown mechanism. Loss of efficacy may occur.
MANAGEMENT: Monitoring of cyclosporine levels during concomitant administration is recommended, as is close observation of the patient for signs of rejection or toxicity when griseofulvin is added to or discontinued from therapy. Dose adjustments may be required.
- Abu-Romeh SH, Rashed A "Ciclosporin A and griseofulvin: another drug interaction." Nephron 58 (1991): 237
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Gengraf (Capsules, Modified), Gengraf
Generic Name: griseofulvin
Brand name: Grifulvin V, Fulvicin P/G, Fulvicin U/F, Gris-PEG, Grisactin Ultra, Grisactin 250, Grisactin 500, Griseofulicin, Griseofulvic
Synonyms: Griseofulvin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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