Gengraf Capsules and Imuran Intravenous
Determining the interaction of Gengraf Capsules and Imuran Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cycloSPORINE together with azaTHIOprine may decrease the effects of cycloSPORINE. Given the risk of organ rejection associated with low cycloSPORINE levels, caution is advised if cycloSPORINE must be taken with azaTHIOprine. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Plasma cyclosporine concentrations may be reduced during coadministration with azathioprine. The mechanism is unknown.
MANAGEMENT: Cyclosporine levels should be monitored when azathioprine is initiated or discontinued in a patient previously stabilized on cyclosporine.
- Grekas DM "Effects of azathioprine on ciclosporin metabolism." Nephron 60 (1992): 489
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Gengraf (Capsules, Modified), Gengraf
Generic Name: azathioprine
Brand name: Azasan, Imuran
Synonyms: Imuran
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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