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Gengraf Capsules and Ursodiol

Determining the interaction of Gengraf Capsules and Ursodiol and the possibility of their joint administration.

Check result:
Gengraf Capsules <> Ursodiol
Relevance: 22.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Bile acid salts may increase the bioavailability of oral cyclosporine. Data have been conflicting. The mechanism and clinical significance are unknown. No action is necessary; however, clinicians should be aware of the possibility of an interaction.

References
  • "Product Information. Neoral Soft Gelatin Capsules (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Gengraf Capsules

Generic Name: cyclosporine

Brand name: Gengraf, Neoral, Sandimmune, Sandimmune

Synonyms: Gengraf (Capsules, Modified), Gengraf

Ursodiol

Generic Name: ursodiol

Brand name: Actigall, Urso, Urso Forte, Urso DS

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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