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Gengraf Capsules and Vancocin HCl

Determining the interaction of Gengraf Capsules and Vancocin HCl and the possibility of their joint administration.

Check result:

Gengraf Capsules <> Vancocin HCl

Relevance: 22.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using cycloSPORINE together with vancomycin can be harmful to the kidneys. Symptoms of kidney damage include swelling, weight gain, feeling short of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, pain in your lower back, and urinating more or less than usual or not at all. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special tests to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The potential nephrotoxic effects of cyclosporine and glycopeptide antibiotics may be additive.

MANAGEMENT: Serum drug concentrations and renal function, including serum creatinine, should be carefully monitored during concurrent administration.

References

Kureishi A, Jewesson PJ, Rubinger M, et al "Double-blind comparison of teicoplanin versus vancomycin in febrile neutropenic patients receiving concomitant tobramycin and piperacillin: effect on cyclosporin A." Antimicrob Agents Chemother 35 (1991): 2246-52
"Product Information. Sandimmune (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.

Gengraf Capsules

Generic Name: cyclosporine

Brand name: Gengraf, Neoral, Sandimmune, Sandimmune

Synonyms: Gengraf (Capsules, Modified), Gengraf

What is Gengraf Capsules?

Vancocin HCl

Generic Name: vancomycin

Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50

Synonyms: Vancocin HCl (Intravenous)

What is Vancocin HCl?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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