Gilteritinib Fumarate and Siliq

• Generic Name: gilteritinib
• Dosage Forms: n.a.
• Other Brand Names: Xospata

For the treatment of relapsed or refractory AML harboring Flt-3 mutation (designated an orphan drug by FDA for this use).

FDA-approved companion diagnostic test (e.g., LeukoStrat CDx Flt-3 mutation assay) required to confirm presence of Flt-3 mutation prior to initiation of therapy.

• Generic Name: brodalumab
• Dosage Forms: injection
• Other Brand Names: Siliq

Siliq (brodalumab) is a monoclonal antibody that blocks certain proteins in the body that can affect inflammation and other immune responses.

Siliq is used to treat moderate to severe plaque psoriasis in adults. It is usually given after other psoriasis medicines have been tried without success.

Siliq is available only from a certified pharmacy under a special program called Siliq REMS. You must be registered in the program and understand the risks and benefits of taking this medicine.