Glasdegib Maleate and Inderal XL

• Generic Name: glasdegib
• Dosage Forms: n.a.
• Other Brand Names: Daurismo

Glasdegib maleate is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy.

Glasdegib maleate has not been studied in patients with the comorbidities of severe renal impairment or moderate-to-severe hepatic impairment.

• Generic Name: propranolol
• Dosage Forms: capsule, extended release
• Other Brand Names: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Inderal XL is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Inderal XL is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.

Hemangeol (Inderal XL oral liquid 4.28 milligrams) is given to infants who are at least 5 weeks old to treat a genetic condition called infantile hemangiomas. Hemangiomas are caused by blood vessels grouping together in an abnormal way. These blood vessels form benign (non-cancerous) growths that can develop into ulcers or red marks on the skin. Hemangiomas can also cause more serious complications inside the body (in the liver, brain, or digestive system).

Inderal XL may also be used for purposes not listed in this medication guide.