Glasdegib Maleate and Librax

• Generic Name: glasdegib
• Dosage Forms: n.a.
• Other Brand Names: Daurismo

Glasdegib maleate is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy.

Glasdegib maleate has not been studied in patients with the comorbidities of severe renal impairment or moderate-to-severe hepatic impairment.

• Generic Name: chlordiazepoxide / clidinium
• Dosage Forms: capsule
• Other Brand Names: Librax, Clindex, Chlordinium

Librax is a capsule containing a combination of chlordiazepoxide and clidinium. Chlordiazepoxide is a benzodiazepine that affects chemicals in the brain that may be unbalanced. Clidinium reduces stomach acid and decreases intestinal spasms.

Librax is a medicine that may be effective in treating stomach ulcers, irritable bowel syndrome, or symptoms related to intestinal infection. Librax is given together with other medications to treat these conditions.

The U.S. Food and Drug Administration has determined that Librax is "possibly" effective in treating these conditions.