Glipizide ER and Maprotiline Hydrochloride

• Generic Name: glipizide
• Dosage Forms: tablet, extended release
• Other Brand Names: Glucotrol, Glucotrol XL, Glipizide XL

Glipizide is an oral diabetes medicine that helps control blood sugar levels by helping your pancreas produce insulin.

Glipizide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Glipizide is not for treating type 1 diabetes.

• Generic Name: maprotiline
• Dosage Forms: n.a.
• Other Brand Names: Ludiomil

Management of depressive disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.

Management of anxiety associated with depression.

Bipolar Disorder

Has been used for the management of acute depressive episodes in bipolar disorder.

However, the American Psychiatric Association (APA) currently does not recommend antidepressant monotherapy for the management of acute depressive episodes in patients with bipolar disorder to avoid precipitation of hypomania or manic episodes. When antidepressants are used in combination with first-line therapies (e.g., lithium, lamotrigine) in patients with bipolar disorder, antidepressants other than TCAs (e.g., bupropion, SSRIs, venlafaxine) generally are preferred.