GlucaGen HypoKit and Levobunolol Hydrochloride
Determining the interaction of GlucaGen HypoKit and Levobunolol Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Beta-blockers may blunt the hyperglycemic reaction to glucagon by interfering with beta-adrenergic-mediated hyperglycemic counter-regulatory mechanisms. No special precautions appear to be necessary.
- Mills GA, Horn JR "B-blockers and glucose control." Drug Intell Clin Pharm 19 (1985): 246-51
- Smith RC, Wilkinson J, Hull RL "Glucagon for propranolol overdose." JAMA 254 (1985): 2412
- Smith RC, Wilkinson DO, Hull RL "Glucagon for propranolol overdose." JAMA 254 (1985): 2412
- Messerli FH, Kuchel O, Tolis G, Hamet P, Fraysse J, Genest J "Effects of B-adrenergic blockade on plasma cyclic AMP and blood sugar responses to glucagon and isoproterenol in man." Int J Clin Pharmacol 14 (1976): 189-94
- Pun KK, Yeung CK, Chak W, et al "Effects of selective and non-selective beta-blockers on the alanine and free fatty acid responses to glucagon challenge in hemodialysis patients." Clin Nephrol 26 (1986): 222-6
Generic Name: glucagon
Brand name: Glucagen, GlucaGen HypoKit, Glucagon Emergency Kit for Low Blood Sugar, Gvoke HypoPen, Gvoke PFS, Baqsimi
Synonyms: GlucaGen HypoKit (injection), GlucaGen
Generic Name: levobunolol ophthalmic
Brand name: Betagan, Akbeta, Levobunolol, Betagan C-Cap
Synonyms: Levobunolol ophthalmic, Levobunolol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- GlucaGen HypoKit-Levobunolol ophthalmic
- GlucaGen HypoKit-Levocarnitine
- GlucaGen HypoKit-Levocarnitine Capsules and Tablets
- GlucaGen HypoKit-Levocarnitine Injection
- GlucaGen HypoKit-Levocarnitine Injection Solution
- GlucaGen HypoKit-Levocarnitine Oral Solution
- Levobunolol Hydrochloride-GlucaGen HypoKit injection
- Levobunolol Hydrochloride-GlucaGen injection
- Levobunolol Hydrochloride-Glucagon
- Levobunolol Hydrochloride-Glucagon Auto-Injectors and Prefilled Syringes
- Levobunolol Hydrochloride-Glucagon Diagnostic Kit
- Levobunolol Hydrochloride-Glucagon Emergency