Glycerol phenylbutyrate and Thalitone

• Generic Name: glycerol phenylbutyrate
• Dosage Forms: n.a.
• Other Brand Names: Ravicti

Glycerol phenylbutyrate binds with other substances in the liver and kidneys to help eliminate nitrogen from the body. Excess nitrogen can cause hyperammonemia (HYE-per-AM-moe-NEE-mee-a), a build-up of ammonia in the blood. Ammonia is very toxic when it circulates in blood and tissues and can cause permanent brain damage, coma, or death.

Glycerol phenylbutyrate helps prevent a build-up of ammonia in the blood in people with urea cycle disorder. glycerol phenylbutyrate is used in adults and children who are at least 2 months old. Glycerol phenylbutyrate will not treat hyperammonemia.

Glycerol phenylbutyrate is usually given together with a low-protein diet and sometimes dietary supplements.

Glycerol phenylbutyrate may also be used for purposes not listed in this medication guide.

• Generic Name: chlorthalidone
• Dosage Forms: tablet
• Other Brand Names:

  Hygroton, Thalitone

Chlorthalidone is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Chlorthalidone is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or treatment with a hormone or steroid medicine.

Chlorthalidone is a diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps to lower blood pressure.

Chlorthalidone is available only with your doctor's prescription.