Glycerol phenylbutyrate and Utibron Neohaler

• Generic Name: glycerol phenylbutyrate
• Dosage Forms: n.a.
• Other Brand Names: Ravicti

Glycerol phenylbutyrate binds with other substances in the liver and kidneys to help eliminate nitrogen from the body. Excess nitrogen can cause hyperammonemia (HYE-per-AM-moe-NEE-mee-a), a build-up of ammonia in the blood. Ammonia is very toxic when it circulates in blood and tissues and can cause permanent brain damage, coma, or death.

Glycerol phenylbutyrate helps prevent a build-up of ammonia in the blood in people with urea cycle disorder. glycerol phenylbutyrate is used in adults and children who are at least 2 months old. Glycerol phenylbutyrate will not treat hyperammonemia.

Glycerol phenylbutyrate is usually given together with a low-protein diet and sometimes dietary supplements.

Glycerol phenylbutyrate may also be used for purposes not listed in this medication guide.

• Generic Name: glycopyrrolate / indacaterol
• Dosage Forms: inhalation capsule
• Other Brand Names: Utibron Neohaler

Utibron inhalation powder contains a combination of glycopyrrolate and indacaterol. Glycopyrrolate is an anticholinergic. Indacaterol is a bronchodilator. These medications work by relaxing muscles in the airways to improve breathing.

Utibron Neohaler is used long term to prevent airflow obstruction or bronchospasm in people with COPD (chronic obstructive pulmonary disease).

Utibron Neohaler is not for use in treating asthma.

Indacaterol may increase the risk of death in people with asthma, but the risk in people with COPD is not known. Talk with your doctor about your individual risk.