Glynase and Maprotiline Hydrochloride

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using maprotiline together with glyBURIDE can increase the effects of glyBURIDE. You should be advised to regularly monitor your blood sugar and counseled on how to recognize and treat hypoglycemia (low blood sugar), which may include symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, and palpitations. You may need a dose adjustment or blood sugar checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Data from a single case report suggest that maprotiline may enhance the hypoglycemic effect of glyburide. The mechanism is unknown.

MANAGEMENT: Patients should be monitored for altered glycemic effect when maprotiline is added to or removed from a patient's regimen. Patients should be advised to regularly monitor their blood sugar, counseled on how to recognize and treat hypoglycemia (e.g., headache, dizziness, drowsiness, nausea, tremor, hunger, weakness, or palpitations), and to notify their physician if it occurs.

Glynase

Generic Name: glyburide

Brand name: DiaBeta, Glynase, DiaBeta, Glynase PresTab, Micronase

Synonyms: n.a.

What is Glynase?

Maprotiline Hydrochloride

Generic Name: maprotiline

Brand name: Ludiomil

Synonyms: Maprotiline

What is Maprotiline Hydrochloride?