Glyxambi and Insulin Degludec (U-200) Prefilled Pens
Determining the interaction of Glyxambi and Insulin Degludec (U-200) Prefilled Pens and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Linagliptin may help control blood glucose levels, which may lead to a reduction in your dosage requirement of insulin degludec or any other diabetic medications you are receiving. Your blood glucose should be closely monitored so that medications may be adjusted accordingly by your doctor. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. Likewise, if linagliptin is discontinued, your blood glucose may increase and hyperglycemia may occur, which may require readjustment of your medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSE: Coadministration of a dipeptidyl peptidase-4 inhibitor with an insulin secretagogue (e.g., sulfonylurea, meglitinide) or insulin may potentiate the risk of hypoglycemia.
MANAGEMENT: A lower dosage of the insulin secretagogue or insulin may be required when used in combination with a dipeptidyl peptidase-4 inhibitor.
- "Product Information. Januvia (sitagliptin)." Merck & Company Inc, West Point, PA.
- "Product Information. Tradjenta (linagliptin)." Boehringer Ingelheim, Ridgefield, CT.
- "Product Information. Onglyza (saxagliptin)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: empagliflozin / linagliptin
Brand name: Glyxambi
Synonyms: n.a.
Generic Name: insulin degludec
Brand name: Tresiba, Tresiba FlexTouch
Synonyms: Insulin degludec, Insulin Degludec
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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