Golimumab and Safinamide Mesylate

• Generic Name: golimumab
• Dosage Forms: n.a.
• Other Brand Names: Simponi, Simponi SmartJect, Simponi Aria

Golimumab is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis. Golimumab is sometimes used with another medicine called methotrexate (Rheumatrex, Trexall).

Golimumab may also be used for purposes not listed in this medication guide.

• Generic Name: safinamide
• Dosage Forms: n.a.
• Other Brand Names: Xadago

Used as an adjunct to levodopa-carbidopa for the symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who experience “off” episodes (i.e., time when drug effect wears off and parkinsonian manifestations return).

Shown to be effective only in combination with levodopa-carbidopa; efficacy of safinamide monotherapy not established.