Golimumab Subcutaneous and Perflutren lipid microsphere Intravenous

• Generic Name: golimumab
• Dosage Forms: n.a.
• Other Brand Names: Simponi, Simponi SmartJect, Simponi Aria

Golimumab injection is used alone or together with other medicines (eg, methotrexate) to treat the symptoms of moderate to severe rheumatoid arthritis and ankylosing spondylitis (arthritis in the spine or backbone). It is also used to treat psoriatic arthritis, which is a type of arthritis that causes pain and swelling in the joints along with patches of scaly skin on some areas of the body.

Golimumab injection is used to treat moderate to severe ulcerative colitis in patients who have been treated with other medicines that did not work well.

Golimumab is available only with your doctor's prescription.

• Generic Name: perflutren
• Dosage Forms: n.a.
• Other Brand Names: Definity, Optison

Perflutren lipid microsphere preparation is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound. Ultrasound is a special kind of diagnostic procedure. It uses high-frequency sound waves to create images or “pictures” of certain areas inside the body. The sound waves produced by the ultrasound equipment can be reflected (bounced off) by different parts of the body, like for example, the heart. As the sound waves return they are electronically converted into images on a television screen. Unlike x-rays, ultrasound does not involve ionizing radiation.

The perflutren lipid microspheres preparation contains very small gas-filled lipid microspheres that reflect the sound waves and help create a better picture. The lipid microsphere preparation is given by injection into a vein before ultrasound to help diagnose problems of the heart.

Perflutren lipid microsphere is to be given only by or under the direct supervision of a doctor with specialized training in ultrasound procedures.