About us Contacts Drug interactions: 390 212
Drug search by name

Good Sense Hair Regrowth Treatment and Trinipatch 0.2

Determining the interaction of Good Sense Hair Regrowth Treatment and Trinipatch 0.2 and the possibility of their joint administration.

Check result:
Good Sense Hair Regrowth Treatment <> Trinipatch 0.2
Relevance: 21.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

After using minoxidil topical, some of the medication may be absorbed into the bloodstream and occasionally produce cardiovascular side effects such as decreases in blood pressure, swelling, and palpitation. Combining it with nitroglycerin or other medications that can also have these effects may increase the risk. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart beat. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Theoretically, topical administration of minoxidil may potentiate the hypotensive effects of systemic minoxidil and other vasodilators. Although systemic absorption of topical minoxidil is generally minimal (approximately 1.6% to 3.9% of an applied dose), adverse cardiovascular effects such as edema, palpitations, blood pressure decreases, and increased pulse rate have been reported in a few patients. Increased systemic absorption may occur when topical minoxidil is used in excess of normally recommended dosages or applied to compromised skin.

MANAGEMENT: Patients prescribed topical minoxidil in combination with systemic vasodilators or peripherally-acting antiadrenergic agents should be monitored for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache.

References
  • Leenen FH, Smith DL, Unger WP "Topical minoxidil: cardiac effects in bald men." Br J Clin Pharmacol 26 (1988): 481-5
  • "Product Information. Rogaine (minoxidil topical)." Pharmacia and Upjohn, Kalamazoo, MI.
Good Sense Hair Regrowth Treatment

Generic Name: minoxidil topical

Brand name: Rogaine, Ronoxidil, Rogaine Extra Strength, Rogaine Women's, Rogaine Men's Extra Strength

Synonyms: Minoxidil topical, Minoxidil (Topical)

Trinipatch 0.2

Generic Name: nitroglycerin

Brand name: Gonitro, Nitrolingual, NitroMist, Nitrostat, Nitro-Time, Gonitro, Minitran, Nitro TD Patch-A, Nitro-Dur, Nitro-Bid, Nitrol Appli-Kit, Rectiv

Synonyms: Nitroglycerin (oral/sublingual), Nitroglycerin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.