Goserelin Acetate and Kalydeco

• Generic Name: goserelin
• Dosage Forms: n.a.
• Other Brand Names: Zoladex

Palliative treatment of advanced prostate cancer. Considered one of several first-line options for hormonal therapy; other options include orchiectomy, estrogens, and antiandrogens.

In clinical studies, goserelin (3.6 mg every 4 weeks) was as effective as orchiectomy. Clinical outcome in patients receiving goserelin 10.8 mg every 12 weeks expected to be similar to that of patients receiving goserelin 3.6 mg every 4 weeks.

Also used as an adjunct to radiation therapy in patients with stage III[C]) prostate cancer.

Treatment of locally confined stage T2b-T4 (B2-C) prostate cancer in conjunction with flutamide and radiation therapy.

Palliative treatment of endometriosis. Experience with goserelin has been limited to women ≥18 years of age who received consecutive therapy (3.6 mg every 4 weeks) for 6 months.

Palliative treatment of advanced breast cancer in premenopausal and perimenopausal women.

Used as an endometrial-thinning agent prior to endometrial ablation procedures for the treatment of dysfunctional uterine bleeding.

• Generic Name: ivacaftor
• Dosage Forms: tablet, film coated; oral granule
• Other Brand Names: Kalydeco

Kalydeco (ivacaftor) is used to treat cystic fibrosis in adults and children who are at least 6 months old and weigh at least 11 pounds (5 kilograms).

Kalydeco is for use only in patients with a specific gene mutation related to cystic fibrosis.

Before you take Kalydeco, you may need a medical test to make sure you have this gene mutation.