Granisetron Transdermal System and Ketoconazole (Systemic)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

In vitro human hepatic microsomal studies indicate that ketoconazole inhibits ring oxidation of granisetron. However, the clinical significance in vivo is unknown, particularly given the wide margin of safety of granisetron.

Granisetron Transdermal System

Generic Name: granisetron

Brand name: Sancuso, Sustol, Kytril

Synonyms: Granisetron

What is Granisetron Transdermal System?

Ketoconazole (Systemic)

Generic Name: ketoconazole

Brand name: Nizoral

Synonyms: Ketoconazole

What is Ketoconazole (Systemic)?