Granisetron Transdermal System and Phenobarbital Oral Solution
Determining the interaction of Granisetron Transdermal System and Phenobarbital Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In a human pharmacokinetic study, hepatic enzyme induction with phenobarbital resulted in a 25% increase in total plasma clearance of intravenous granisetron. Given the wide margin of safety of granisetron, the clinical significance of this change is unknown.
- "Product Information. Kytril (granisetron)." SmithKline Beecham, Philadelphia, PA.
Generic Name: granisetron
Brand name: Sancuso, Sustol, Kytril
Synonyms: Granisetron
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: Phenobarbital, PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Granisetron Transdermal System-Phenobarbital Sodium
- Granisetron Transdermal System-Phenobarbital Sodium Injection
- Granisetron Transdermal System-Phenobarbital Tablets
- Granisetron Transdermal System-Phenobarbital with Belladonna Alkaloids Elixir
- Granisetron Transdermal System-Phenohytro
- Granisetron Transdermal System-Phenohytro Elixir
- Phenobarbital Oral Solution-Granisol
- Phenobarbital Oral Solution-Granix
- Phenobarbital Oral Solution-Grass Pollen Allergen Extract (5 Grass Extract)
- Phenobarbital Oral Solution-Grass Pollen Allergen Extract (Timothy Grass)
- Phenobarbital Oral Solution-Grastek
- Phenobarbital Oral Solution-Green tea