Griseofulvin Tablets and Orphenadrine, aspirin, and caffeine
Determining the interaction of Griseofulvin Tablets and Orphenadrine, aspirin, and caffeine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One pediatric case report has suggested that griseofulvin may decrease serum salicylate (aspirin) concentrations. The mechanism suggested by the authors is interference with salicylate absorption. The authors have recommended that griseofulvin be avoided if possible when therapy with anti-inflammatory doses of salicylate are required. If these drugs must be given together, staggered doses and careful monitoring of salicylate levels are recommended.
- Phillips KR, Wideman SD, Cochran EB, Becker JA "Griseofulvin significantly decreases serum salicylate concentrations." Pediatr Infect Dis J 12 (1993): 350-2
Generic Name: griseofulvin
Brand name: Grifulvin V, Fulvicin P/G, Fulvicin U/F, Gris-PEG, Grisactin Ultra, Grisactin 250, Grisactin 500, Griseofulicin, Griseofulvic
Synonyms: Griseofulvin
Generic Name: aspirin / caffeine / orphenadrine
Brand name: Norgesic Forte, Orphengesic Forte, Norgesic, Orphengesic
Synonyms: Aspirin, caffeine, and orphenadrine, Orphenadrine Aspirin Caffeine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Griseofulvin Tablets-Orphenate
- Griseofulvin Tablets-Orphengesic
- Griseofulvin Tablets-Orphengesic Forte
- Griseofulvin Tablets-Orsythia
- Griseofulvin Tablets-Ortho D
- Griseofulvin Tablets-Ortho Evra
- Orphenadrine, aspirin, and caffeine-Griseofulvin Ultramicrosize Tablets
- Orphenadrine, aspirin, and caffeine-Guaiatussin AC
- Orphenadrine, aspirin, and caffeine-Guaifen DAC
- Orphenadrine, aspirin, and caffeine-Guaifenesin AC Liquid
- Orphenadrine, aspirin, and caffeine-Guaifenesin and Codeine
- Orphenadrine, aspirin, and caffeine-Guaifenesin and Dextromethorphan Capsules and Tablets