Guaifenesin, hydrocodone, and pseudoephedrine and Vasoflex HD
Determining the interaction of Guaifenesin, hydrocodone, and pseudoephedrine and Vasoflex HD and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Acidic urine increases the elimination of ephedrine and pseudoephedrine and decreases the elimination half-life. The clinical significance is unknown. The therapeutic effects of these agents may be decreased.
- Wilkinson GR, Beckett AH "Absorption metabolism and excretion of the ephedrines in man. I. The influence of urinary pH and urine volume output." J Pharmacol Exp Ther 162 (1968): 139-47
- Brater DC, Kaojarern S, Benet LZ, et al "Renal excretion of pseudoephedrine." Clin Pharmacol Ther 28 (1980): 690-4
- Kuntzman RG, Tsai I, Brand L, Mark LC "The influence of urinary pH on the plasma half-life of pseudoephedrine in man and dog and a sensitive assay for its determination in human plasma." Clin Pharmacol Ther 12 (1971): 62-7
Generic Name: guaifenesin / hydrocodone / pseudoephedrine
Brand name: Entex HC, Hycofenix, Su-Tuss HD Elixir, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Duratuss HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Pseudatex HC
Synonyms: Hydrocodone, Pseudoephedrine, and Guaifenesin
Generic Name: ascorbic acid
Brand name: Acerola, Ascorbic Acid Quick Melts, C/Rose Hips, Cecon, Cemill 500, C-Time, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vasoflex HD, Vicks Vitamin C Drops, Vitamin C, Cenolate, Mega-C-Acid Plus, Cee-500, C-500-Gr, Centrum Singles-Vitamin C, Ascot, Cevi-Bid, Vitamin C TR, Vitamin C with Rose Hips, Cemill 1000, Ascor L NC, Ascor, Ascor L 500, Betac, Cemill, Protexin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasofrinic Dh
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasopressin
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasopressin (IM or Subcutaneous)
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasopressin (IV)
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasopressin Injection
- Guaifenesin, hydrocodone, and pseudoephedrine-Vasostrict
- Vasoflex HD-Guaifenesin, Pseudoephedrine, and Codeine
- Vasoflex HD-Guaifenesin, Pseudoephedrine, and Dextromethorphan
- Vasoflex HD-Guaifenesin, Pseudoephedrine, and Dextromethorphan Liquid
- Vasoflex HD-Guaifenesin, Pseudoephedrine, and Dextromethorphan Tablets and Capsules
- Vasoflex HD-Guaifenesin-DM NR
- Vasoflex HD-Guaifenex