Guanfacine Extended-Release Tablets and Nortriptyline Solution
Determining the interaction of Guanfacine Extended-Release Tablets and Nortriptyline Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using nortriptyline together with guanFACINE can decrease the effects of guanFACINE. Talk with your doctor before using nortriptyline and guanFACINE together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: One case report suggests that tricyclic antidepressants may decrease the antihypertensive effect of guanfacine. The mechanism is unknown.
MANAGEMENT: The patient's blood pressure should be monitored during concomitant therapy and after discontinuation or dose change of the antidepressant. An alternative antihypertensive (e.g., beta adrenergic blocking agent, diuretic) may be considered.
- Buckley M, Feely J "Antagonism of antihypertensive effect of guanfacine by tricyclic antidepressants." Lancet 337 (1991): 1173-4
Generic Name: guanfacine
Brand name: Intuniv, Tenex
Synonyms: Guanfacine, GuanFACINE
Generic Name: nortriptyline
Brand name: Pamelor, Aventyl HCl, Aventyl
Synonyms: Nortriptyline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Guanfacine Extended-Release Tablets-Norvasc
- Guanfacine Extended-Release Tablets-Norvir
- Guanfacine Extended-Release Tablets-Norvir (Ritonavir Capsules)
- Guanfacine Extended-Release Tablets-Norvir (Ritonavir Oral Solution)
- Guanfacine Extended-Release Tablets-Norvir (Ritonavir Powder Packets)
- Guanfacine Extended-Release Tablets-Norvir (Ritonavir Tablets)
- Nortriptyline Solution-Guanfacine Tablets
- Nortriptyline Solution-Guanidine
- Nortriptyline Solution-Guar Gum
- Nortriptyline Solution-Guiadrine DX
- Nortriptyline Solution-Guiatex PE
- Nortriptyline Solution-Gumsol