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Guar Gum and Lanoxicaps

Determining the interaction of Guar Gum and Lanoxicaps and the possibility of their joint administration.

Check result:
Guar Gum <> Lanoxicaps
Relevance: 01.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Concurrent administration of guar gum has been reported to reduce the rate but not the extent of digoxin absorption by prolonging gastric retention. Long-term administration of guar gum is not expected to interfere with the clinical effects of digoxin.

References
  • Huupponen R, Seppala P, Iisalo E "Effect of guar gum, a fibre preparation, on digoxin and penicillin absorption in man." Eur J Clin Pharmacol 26 (1984): 279-81
  • Fugh-Berman A "Herb-drug interactions." Lancet 355 (2000): 134-8
Guar Gum

Generic Name: guar gum

Brand name:

Synonyms: n.a.

Lanoxicaps

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: Lanoxicaps (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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