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Gvoke Injection and Timoptic

Determining the interaction of Gvoke Injection and Timoptic and the possibility of their joint administration.

Check result:

Gvoke Injection <> Timoptic

Relevance: 06.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Beta-blockers may blunt the hyperglycemic reaction to glucagon by interfering with beta-adrenergic-mediated hyperglycemic counter-regulatory mechanisms. No special precautions appear to be necessary.

References

Mills GA, Horn JR "B-blockers and glucose control." Drug Intell Clin Pharm 19 (1985): 246-51
Smith RC, Wilkinson J, Hull RL "Glucagon for propranolol overdose." JAMA 254 (1985): 2412
Smith RC, Wilkinson DO, Hull RL "Glucagon for propranolol overdose." JAMA 254 (1985): 2412
Messerli FH, Kuchel O, Tolis G, Hamet P, Fraysse J, Genest J "Effects of B-adrenergic blockade on plasma cyclic AMP and blood sugar responses to glucagon and isoproterenol in man." Int J Clin Pharmacol 14 (1976): 189-94
Pun KK, Yeung CK, Chak W, et al "Effects of selective and non-selective beta-blockers on the alanine and free fatty acid responses to glucagon challenge in hemodialysis patients." Clin Nephrol 26 (1986): 222-6

Gvoke Injection

Generic Name: glucagon

Brand name: Glucagen, GlucaGen HypoKit, Glucagon Emergency Kit for Low Blood Sugar, Gvoke HypoPen, Gvoke PFS, Baqsimi

Synonyms: Gvoke HypoPen (injection)

What is Gvoke Injection?

Timoptic

Generic Name: timolol ophthalmic

Brand name: Betimol, Istalol, Timoptic Ocudose, Timoptic Ocumeter, Timoptic Ocumeter Plus, Timoptic-XE, Timoptic

Synonyms: Timoptic Ocumeter

What is Timoptic?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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