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Half Lytely and Bisacodyl Lemon Lime and TargaDOX

Determining the interaction of Half Lytely and Bisacodyl Lemon Lime and TargaDOX and the possibility of their joint administration.

Check result:

Half Lytely and Bisacodyl Lemon Lime <> TargaDOX

Relevance: 19.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sodium bicarbonate together with doxycycline may decrease the effects of doxycycline. Administration of sodium bicarbonate and doxycycline should be separated by three to four hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Alkalinization of the urine may decrease the plasma concentration of some tetracyclines. The mechanism is not completely understood, but may involve increased renal elimination of tetracyclines when the urine becomes alkalinized. Information is available for doxycycline, tetracycline, and sodium bicarbonate only.

MANAGEMENT: If these drugs must be used together, an alternating dosing schedule is recommended (three to four hours apart).

References

Elliott GR "Sodium bicarbonate and oral tetracycline." Clin Pharmacol Ther 13 (1972): 459
Jaffe JM, Colaizzi JI, Poust RI, McDonald RH Jr "Effect of altered urinary pH on tetracycline and doxycycline excretion in humans." J Pharmacokinet Biopharm 1 (1973): 267-82
Jaffe JM, Poust RI, Feld SL, Colaizzi JL "Influence of repetitive dosing and altered urinary pH on doxycycline excretion in humans." J Pharm Sci 63 (1974): 1256-60

Half Lytely and Bisacodyl Lemon Lime

Generic Name: bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride

Brand name: Half Lytely and Bisacodyl Lemon Lime, HalfLytely and Bisacodyl, HalfLytely and Bisacodyl with Flavor Packs, GaviLyte-H and Bisacodyl with Flavor Packs

Synonyms: HalfLytely and Bisacodyl

What is Half Lytely and Bisacodyl Lemon Lime?

TargaDOX

Generic Name: doxycycline

Brand name: Acticlate, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, Monodox, Morgidox, Oraxyl, TargaDOX, Vibramycin, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Oracea, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Doxy 100, TargaDOX

Synonyms: Targadox

What is TargaDOX?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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