Haloperidol Decanoate and Phenytoin Infatabs
Determining the interaction of Haloperidol Decanoate and Phenytoin Infatabs and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenytoin together with haloperidol may decrease the effects of haloperidol. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Hydantoins may significantly decrease serum butyrophenone concentrations. The mechanism may be induction of CYP450 hepatic metabolism.
MANAGEMENT: Close observation for decreased neuroleptic effect is indicated during concurrent use and for increased or adverse effects after phenytoin is discontinued.
- Linnoila M, Viukari M, Vaisanen K, Auvinen J "Effect of anticonvulsants on plasma haloperidol and thioridazine levels." Am J Psychiatry 137 (1980): 819-21
Generic Name: haloperidol
Brand name: Haldol, Haldol Decanoate
Synonyms: Haloperidol
Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Phenytoin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Haloperidol Decanoate-Phenytoin injection
- Haloperidol Decanoate-Phenytoin Intravenous
- Haloperidol Decanoate-Phenytoin Oral Suspension
- Haloperidol Decanoate-Phenytoin Sodium
- Haloperidol Decanoate-Phenytoin Sodium, Prompt injection
- Haloperidol Decanoate-Phenytoin Suspension
- Phenytoin Infatabs-Haloperidol Decanoate Injection
- Phenytoin Infatabs-Haloperidol injection
- Phenytoin Infatabs-Haloperidol Intramuscular
- Phenytoin Infatabs-Haloperidol Lactate
- Phenytoin Infatabs-Haloperidol Oral Solution
- Phenytoin Infatabs-Haloperidol Oral Solution, Concentrate