Halothane and Rifadin IV

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using halothane together with rifAMPin. This can cause serious side effects that may affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: The hepatotoxic effects of rifampin and isoniazid appear to be increased when these drugs are administered together after halothane anesthesia. Cases of hepatotoxicity and hepatic encephalopathy, one of which was fatal, have been reported. A similar reaction may occur with rifabutin. The mechanism and causality have not been definitely determined since rifampin, isoniazid or halothane alone are potentially hepatotoxic.

MANAGEMENT: Until more information is available, it is best to avoid this combination after halothane anesthesia.

Halothane

Generic Name: halothane

Brand name:

Synonyms: n.a.

What is Halothane?

Rifadin IV

Generic Name: rifampin

Brand name: Rifadin IV, Rifadin, Rimactane

Synonyms: n.a.

What is Rifadin IV?