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Halothane and Sudafed PE Cold & Cough

Determining the interaction of Halothane and Sudafed PE Cold & Cough and the possibility of their joint administration.

Check result:
Halothane <> Sudafed PE Cold & Cough
Relevance: 08.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before you undergo any procedure where halothane may be used, let your doctor know if you are currently using phenylephrine. Combining these medications may cause irregular heart rhythm. You should be closely monitored by the doctor during the procedure, and the dosage of phenylephrine adjusted as necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The combination of phenylephrine and halothane may increase the risk of ventricular irritability and cardiac arrhythmias. Adverse events have been reported in anesthetized patients after administration of phenylephrine ophthalmic drops.

MANAGEMENT: This combination should be avoided or used very cautiously and the patient's hemodynamic status should be closely monitored.

References
  • "Product Information. Neo-Synephrine (phenylephrine)." Abbott Pharmaceutical, Abbott Park, IL.
  • Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Halothane

Generic Name: halothane

Brand name:

Synonyms: n.a.

Sudafed PE Cold & Cough

Generic Name: acetaminophen / dextromethorphan / guaifenesin / phenylephrine

Brand name: DayQuil Severe Cold & Flu, Delsym Cough Plus Cold Day Time, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Fast-Max Severe Cold, Sudafed PE Cold & Cough, Tylenol Cold & Flu Severe, Tylenol Cold Multi-Symptom Severe, Mucinex Sinus-Max, Sudafed PE Cold/Cough, Tylenol Cold Head Congestion, Tylenol Cold Multi Symptom, Tylenol Cold/Flu Severe, Vicks DayQuil Severe Cold/Flu

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction