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Halothane and Theo-Dur

Determining the interaction of Halothane and Theo-Dur and the possibility of their joint administration.

Check result:

Halothane <> Theo-Dur

Relevance: 08.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using halothane together with theophylline may increase the risk of cardiac side effects such as irregular heart rhythm. Before undergoing surgical procedures where halothane may be used, let your doctor know if you are currently receiving treatment with theophylline. Your doctor will determine whether this combination is safe for you and monitor you for any potential complications during the procedure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The administration of halothane following theophylline administration has been reported to result in ventricular tachycardia and, in one case, ventricular fibrillation. Halothane increases the arrhythmogenic potential of catecholamines. Theophylline appears to enhance the release of catecholamines.

MANAGEMENT: This combination should be avoided if possible. Halothane may interact in a similar manner with other methylxanthines.

References

Roizen MF, Stevens WC "Multiform ventricular tachycardia due to the interaction of aminophylline and halothane." Anesth Analg 57 (1978): 738-41
Richards W, Thompson J, Lewis G, et al "Cardiac arrest associated with halothane anesthesia in a patient receiving theophylline." Ann Allergy 61 (1988): 83-4

Halothane

Generic Name: halothane

Brand name:

Synonyms: n.a.

What is Halothane?

Theo-Dur

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Theo-Dur (Oral)

What is Theo-Dur?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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