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Helidac and Prenatal 19

Determining the interaction of Helidac and Prenatal 19 and the possibility of their joint administration.

Check result:

Helidac <> Prenatal 19

Relevance: 12.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using bismuth subsalicylate together with tetracycline may decrease the effects of tetracycline. Administration of tetracycline and bismuth subsalicylate should be separated by two to three hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Administration of a bismuth-containing preparation within two to three hours of a tetracycline may significantly decrease serum tetracycline concentrations. Data are available for tetracycline and doxycycline. The proposed mechanism is chelation of tetracycline by bismuth.

MANAGEMENT: Administration of a tetracycline and bismuth-containing preparation should be separated by two to three hours. Patients should be monitored for diminished tetracycline efficacy.

References

"Product Information. Nuzyra (omadacycline)." Paratek Pharmaceuticals, Inc., Boston, MA.
Albert KS, Welch RD, DeSante KA, DiSanto AR "Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture." J Pharm Sci 68 (1979): 586-8
Ericsson CD, Feldman S, Pickering LK, Cleary TG "Influence of subsalicylate bismuth on absorption of doxycycline." JAMA 247 (1982): 2266-7
"Product Information. Seysara (sarecycline)." Allergan Inc, Irvine, CA.

Helidac

Generic Name: bismuth subsalicylate / metronidazole / tetracycline

Brand name:

Synonyms: Helidac (Oral)

What is Helidac?

Prenatal 19

Generic Name: multivitamin, prenatal

Brand name: A-Free Prenatal, Azesco, CitraNatal 90 DHA, CitraNatal Assure, CitraNatal B-Calm, Materna, Pramilet FA, Stuartnatal Plus, Natalins Rx, Norlac RX, Neo-Forte, Mynatal, Zenate Advanced Formula, Prenatal MR 90, O-Cal-FA, Equi-Natal Plus, Pan OB Forte, Hi-Nate 90, Lactocal-F, Maternity-90, Prenazyme 1+1, Pre-H-Cal, Femnatal, Vynatal 1 Plus 1, Par-F, Maternity, Niferex PN Forte, Prenavite, Mynatal PN, Obnate 90, Maternal 90, Mynatal Rx, PreCare, Natarex, Ternamar, Aminatal Plus, Elemental Iron-90, Mynatal PN Forte, Mynatal FC, Mynate 90 Plus, Vitamed Prenatal Formula, Zitamin, Preterna, Vernate, Vernate Advanced, Prenate 90, Aminate, Mission Prenatal Rx, Niferex-PN, Marnatal-F, Prenate Ultra, Prenatal Z Advanced Formula, Prenatal Plus, Zenate Prenatal, NatalCare, Prenatal Plus with Beta-Carotene, Prenatal Rx, Maternity plus Beta Carotene, Equi-Natal M, Equi-Natal Rx, Equinatal 90, Equi-Natal Z, Natalcare Pic Forte, Natalcare Pic, Natalins, Stuart Prenatal with Beta Carotene, Prenatal MR 90 Fe, Aminatal Plus One, Aminate with 90 mg Iron, Ultra NatalCare, Prenatal S, Natafort, Nestabs, Nestabs CBF, Vitafol PN, Fem-Natal, Ami-Natal Plus One Improved, Aminatal Plus New Formula, Prenatal Plus with 27 mg Iron, Obegyn, Mission Prenatal, Mission Prenatal FA, Mission Prenatal HP, Mynatal Z, Mynatal Plus, Mynatal Ultracap, Prenatal Plus Iron, Prenatal 1 Plus 1, Natalcare Plus, Prenatal MTR with Selenium, Natalcare Rx, Prenavite FC, Prenavite PC, Chromagen OB, Natatab CFe, Natatab FA, Vitelle Nestabs OTC, NataChew, Premesis Rx, Prenate Advanced Formula, Precare Conceive, Citracal Prenatal Rx, Advanced NatalCare, NutriNate, Nestabs Rx, Stuartnatal Plus 3, Strongstart, Anemagen OB, Ultra-Natal, NatalCare Three, Natatab Rx, Equi-Natal Care, Inatal Advance, Inatal Ultra, Maternity Vitamin Low Iron, Ob-20, Prenatabs CBF, Prenatal Rx Low Iron, Vinate 90, Vinate M, Vinate Ultra, Prenate GT, Ferrex PC Forte, Trinate, Prenatal AD, Prenatal 19, Natalcare, Prenatal H, Duet Chewable, Natalfirst, Natelle, Cenogen Ultra, Prenatal-U, Nestabs FA, Vinate GT, Natafolic-PN, Cal-Nate, Icar Prenatal, Prenate Advance, Novastart, Novanatal, Natacaps, O-Cal Prenatal, NatalCare Advanced-RF, Duet DHA, Prenatabs OBN, Icare Prenatal Rx, Vinatal 600, Nutrispire, PrimaCare One, PrenaFirst, Natafolic-OB, , Choice-OB+DHA, Select-OB+DHA, Stuart One

Synonyms: PreNatal 19

What is Prenatal 19?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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