Hemangeol and Mekinist

• Generic Name: propranolol
• Dosage Forms: oral solution
• Other Brand Names: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Hemangeol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Hemangeol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.

Hemangeol (Hemangeol oral liquid 4.28 milligrams) is given to infants who are at least 5 weeks old to treat a genetic condition called infantile hemangiomas. Hemangiomas are caused by blood vessels grouping together in an abnormal way. These blood vessels form benign (non-cancerous) growths that can develop into ulcers or red marks on the skin. Hemangiomas can also cause more serious complications inside the body (in the liver, brain, or digestive system).

Hemangeol may also be used for purposes not listed in this medication guide.

• Generic Name: trametinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Mekinist

Mekinist (trametinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Mekinist is used alone or in combination with another medicine called dabrafenib (Tafinlar) to treat certain types of cancer in people who have a "BRAF" gene mutation.

Mekinist is for use in treating:

• melanoma (skin cancer) that cannot be treated with surgery or has spread to other parts of the body, or to prevent melanoma from coming back after surgery;

• non-small cell lung cancer that has spread to other parts of the body; or

• advanced or metastatic thyroid cancer that has spread and for which there are no other treatment options.