Hemocyte Oral and Idhifa
Determining the interaction of Hemocyte Oral and Idhifa and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Enasidenib may alter the blood levels of medroxyPROGESTERone in some patients. Be alert to potential changes in the effects of medroxyPROGESTERone. Patients taking oral contraceptives may have increased side effects from the contraceptive or experience breakthrough bleeding or even unintended pregnancy. Patients taking hormone replacement for menopause may have increased side effects from the hormone treatment or increased menopausal symptoms. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with enasidenib may alter the plasma concentrations of hormonal contraceptives. In vitro, enasidenib has been found to both inhibit and induce CYP450 3A4, the isoenzyme primarily responsible for the metabolic clearance of contraceptive hormones. The clinical significance is unknown.
MANAGEMENT: Because use of enasidenib may be associated with fetal harm, it is important that patients not become pregnant during treatment. It may be advisable to monitor patients for potentially altered effects of their hormonal contraceptive during and after treatment with enasidenib. Input from a gynecologist or similar expert on adequate contraception, including emergency contraception, should be sought as needed. Intrauterine systems are unlikely to be significantly affected because of their local action.
- "Product Information. Idhifa (enasidenib)." Celgene Corporation, Summit, NJ.
Generic Name: conjugated estrogens / medroxyprogesterone
Brand name: Premphase, Prempro
Synonyms: Conjugated estrogens and medroxyprogesterone, Estrogens (Conjugated/Equine) and Medroxyprogesterone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hemocyte Oral-Iferex 150
- Hemocyte Oral-Ifex
- Hemocyte Oral-Ifex/Mesnex Kit
- Hemocyte Oral-Ifosfamide
- Hemocyte Oral-Ifosfamide and Mesna Injection
- Hemocyte Oral-Ifosfamide Intravenous
- Idhifa-Hemocyte Plus (Vitamin B Complex and Iron Combinations Tablets and Capsules)
- Idhifa-Hemocyte Plus (Vitamins (Multiple/Oral))
- Idhifa-Hemocyte-F
- Idhifa-Hemofil M
- Idhifa-Hemofil-M human
- Idhifa-Hemorid rectal