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Heparin and Dextrose and Palifermin

Determining the interaction of Heparin and Dextrose and Palifermin and the possibility of their joint administration.

Check result:
Heparin and Dextrose <> Palifermin
Relevance: 20.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using heparin together with palifermin. Using these medications together may decrease the effects of heparin. If heparin is used to maintain an IV line, saline should be used to rinse the line prior to and after palifermin administration. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without talking to your doctor first.

Professional:

GENERALLY AVOID: Palifermin has been shown to bind to heparin in vitro.

MANAGEMENT: If heparin is used to maintain an IV line, saline should be used to rinse the line prior to and after palifermin administration.

References
  • "Product Information. Kepivance (palifermin)." Shire US Inc, Florence, KY.
Heparin and Dextrose

Generic Name: heparin

Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush

Synonyms: Heparin Injection, Heparin

Palifermin

Generic Name: palifermin

Brand name: Kepivance

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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