Heparin and Sodium Chloride and Prostin VR
Determining the interaction of Heparin and Sodium Chloride and Prostin VR and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using heparin together with alprostadil may increase the risk of bleeding. Call your doctor promptly if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of heparin with alprostadil may result in additive anticoagulant effects and increase the risk of bleeding. Alprostadil's pharmacologic effects include inhibition of platelet aggregation.
MANAGEMENT: The manufacturers recommend caution when alprostadil is administered to neonates with bleeding tendencies.
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Prostin VR Pediatric Sterile Solution (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: heparin
Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush
Synonyms: Heparin Injection, Heparin
Generic Name: alprostadil
Brand name: Caverject, Caverject Impulse, Edex, Muse, Prostin VR Pediatric, Edex Refill
Synonyms: Alprostadil (injectable and transurethral), Alprostadil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Heparin and Sodium Chloride-Prostin VR Pediatric
- Heparin and Sodium Chloride-Prostin VR Pediatric Intravenous
- Heparin and Sodium Chloride-ProtectIron
- Heparin and Sodium Chloride-Protegra
- Heparin and Sodium Chloride-Protein C Concentrate
- Heparin and Sodium Chloride-Protein C Concentrate (Human)
- Prostin VR-Heparin flush
- Prostin VR-Heparin Intravenous, Subcutaneous
- Prostin VR-Heparin Lock flush
- Prostin VR-Heparin Lock Flush Solution
- Prostin VR-Heparin Sodium
- Prostin VR-Heparin, Concentrate