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Heparin Lock Flush Solution and Ticlid

Determining the interaction of Heparin Lock Flush Solution and Ticlid and the possibility of their joint administration.

Check result:
Heparin Lock Flush Solution <> Ticlid
Relevance: 21.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using heparin together with ticlopidine can cause you to bleed more easily. Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Although therapy with heparin and ticlopidine often overlaps in clinical practice, the potential for additive anticoagulant effects and increased risk of bleeding should be considered.

MANAGEMENT: The manufacturer recommends that heparin be discontinued before initiating ticlopidine therapy. Patients who are to receive these drugs concomitantly should be closely monitored for signs of bleeding. Clinical trials have reported the concomitant use of heparin and ticlopidine in patients undergoing coronary stenting.

References
  • "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc, Palo Alto, CA.
Heparin Lock Flush Solution

Generic Name: heparin

Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush

Synonyms: Heparin Injection, Heparin

Ticlid

Generic Name: ticlopidine

Brand name: Ticlid

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction