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Histex and Hylenex Recombinant

Determining the interaction of Histex and Hylenex Recombinant and the possibility of their joint administration.

Check result:
Histex <> Hylenex Recombinant
Relevance: 24.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Larger amounts of hyaluronidase may be required to achieve equivalent dispersing effects if patients are concomitantly receiving large doses of salicylates, cortisone, ACTH, estrogens, or antihistamines. These drugs may render tissues partially resistant to the dispersing action of hyaluronidase.

References
  • "Product Information. Vitrase (hyaluronidase)." Bausch and Lomb, Rochester, NY.
Histex

Generic Name: chlorpheniramine / pseudoephedrine

Brand name: Allerest Maximum Strength, Dicel, LoHist-D, SudoGest Sinus & Allergy, Triaminic Cold and Allergy, Clorfed, Histalet, Fedahist, Tanafed, Novafed A, Chlorafed HS. Timecelles, Codimal-LA, Kronofed-A-Jr, Rescon, Rescon JR, Dura-Tap/PD, Fedahist Timecaps, Orlenta, Chlorphedrin SR, Colfed-A, D-Amine-SR, Deconomed SR, Pseudocot-C, Duralex, Rinade-BID, Suphenamine-SR, Isophen-DF, Kronofed-A, ND Clear, Chlordrine SR, Anamine TD, Time-Hist, Chlorafed Timecelles, Brexin LA, Rescon-Ed, Deconamine SR, Pseudochlor, Cophene No. 2, Anaplex, Anamine, Klerist-D, Codimal-LA Half, Fedahist Gyrocaps, Deconamine, Clorfed II, Curaler, Sudafed Plus, Chlorafed, Histafed LA, Chlor Trimeton Allergy Decongestant, Aller-Chlor Decongestant, Sudogest Plus, Ryna Liquid, Genaphed Plus, Dayquil Allergy, Hayfebrol Liquid, Suphedrine Plus, Atrohist Pediatric Capsule, Histex, Triaminic Softchew Cold and Allergy, Chlor-Trimeton Allergy Decongestant SR, Tavist-DA, Biohist LA, Dynahist-ER Pediatric, Pediacare Cold and Allergy, CP-Tannic, Durafed, Histade, Duotan, Mintex, QDall, Suclor, Sudafed Sinus/Allergy, Re2+30, Sudal-12, Pediox Chewable, C-Phed Tannate, De-Congestine, Sudal-12 Chewable, Sudal-12 Tannate, SudaHist, Triaminic Softchews Allergy Nose & Congestion, Duratuss DA, Neutrahist Drops, AccuHist Drops, Sudogest Cold & Allergy, Dicel Chewables, PediaCare Cold/Allergy

Synonyms: Chlorpheniramine and pseudoephedrine, Chlorphen Mal, Pseudoeph HCl

Hylenex Recombinant

Generic Name: hyaluronidase

Brand name: Amphadase, Hylenex, Vitrase, Wydase, Hydase

Synonyms: Hyaluronidase (injection), Hyaluronidase

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction