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Horizant and Leader Heartburn Relief

Determining the interaction of Horizant and Leader Heartburn Relief and the possibility of their joint administration.

Check result:

Horizant <> Leader Heartburn Relief

Relevance: 18.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Cimetidine may decrease the clearance of gabapentin by about 14%. The creatinine clearance has also been reported to be decreased by about 10% when cimetidine and gabapentin are coadministered. The mechanism of this interaction is unknown. This interaction is probably not clinically significant.

References

"Product Information. Neurontin (gabapentin)." Parke-Davis, Morris Plains, NJ.

Horizant

Generic Name: gabapentin enacarbil

Brand name: Horizant

Synonyms: n.a.

What is Horizant?

Leader Heartburn Relief

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: n.a.

What is Leader Heartburn Relief?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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