Horizant and Phenytoin Oral Suspension

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Before taking phenytoin, tell your doctor if you also use gabapentin. This combination may increase the phenytoin levels in your body. This combination may cause drowsiness, visual problems, seizures, changes in behavior, nausea, or poor muscle coordination. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special test if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

MONITOR: One case report described elevated serum phenytoin concentrations in a patient also receiving gabapentin; however, the manufacturer reports that the two drugs do not affect each other. The mechanism of the interaction is unknown.

MANAGEMENT: The clinician may consider closer clinical and laboratory monitoring of patients receiving gabapentin and phenytoin. The dose of phenytoin should be adjusted as needed. Patients should be advised to notify their physician if they experience signs of phenytoin toxicity (e.g., dizziness, imbalance, dysarthria, nystagmus, or ataxia).

Horizant

Generic Name: gabapentin enacarbil

Brand name: Horizant

Synonyms: n.a.

What is Horizant?

Phenytoin Oral Suspension

Generic Name: phenytoin

Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: Phenytoin

What is Phenytoin Oral Suspension?