Humatrope and Tadalafil Tablets (Cialis)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Somatropin may reduce the blood levels and effects of tadalafil. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of tadalafil, which is primarily metabolized by the isoenzyme. Rifampin (600 mg daily), a potent CYP450 3A4 inducer, has been reported to decrease tadalafil peak plasma concentration (Cmax) and systemic exposure (AUC) from a single 10 mg dose by 46% and 88%, respectively, compared to administration of the drug alone.

MANAGEMENT: For the treatment of benign prostatic hyperplasia and erectile dysfunction, no dosage adjustment of tadalafil is warranted during coadministration with CYP450 3A4 inducers. However, the possibility of diminished pharmacologic effects of tadalafil should be considered. For the treatment of pulmonary arterial hypertension, use of tadalafil should be avoided in patients chronically taking potent inducers of CYP450 3A4.

Humatrope

Generic Name: somatropin

Brand name: Genotropin, Humatrope, Norditropin FlexPro Pen, Nutropin AQ NuSpin 10, Nutropin AQ Pen 10 Cartridge, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, Genotropin Miniquick, Norditropin Nordiflex Pen, Tev-Tropin, Nutropin, Norditropin, Nutropin AQ, Nutropin Depot, Norditropin Cartridge, Saizen Click-Easy, Omnitrope Pen 5 Cartridge, HumatroPen, Omnitrope Pen 10 Cartridge, Nutropin AQ Pen 20 Cartridge, Nutropin AQ NuSpin 5, Nutropin AQ NuSpin 20, Saizen Kit

Synonyms: n.a.

What is Humatrope?

Tadalafil Tablets (Cialis)

Generic Name: tadalafil

Brand name: Adcirca, Cialis, Alyq

Synonyms: Tadalafil

What is Tadalafil Tablets (Cialis)?